If you understand the Physics of what's going on (I have a degree in this), it absolutely is.
As you play different notes, the active string length changes - what that means is that you can't place the pickup so that it always ignores the 5th harmonic, but when the string is 5x longer than the distance from the bridge to the pickup, it will absolutely do that. Why did I choose that example? Because..if you pick up a single coil/'51 style P bass, most of those have their pickup nailed dead on to 1/5th the distance from the bridge to the nut (most accurate on the G string). So, if you play that harmonic on the G string (just behind the 4th fret), you can hear it acoustically - the string is absolutely vibrating at that frequency. Now, plug in and play it again - you will
not hear that harmonic in the electrical output - it is
completely cancelled. The string has a node there for that harmonic (it isn't moving in that location) - so, if you "listen" there with a pickup located at that spot, you simply won't hear that harmonic.
Here is a frequency response of the comb filter resulting from pickup placement of the A string on a 34 inch bass - two curves, one is a P, the other a J:
The curve has the same shape for every string, but is shifted left or right, depending on the tuning of the string. You'll note a few things:
1) The fundamentals are all in that slope to the left on the graph - the lowest notes on any string have less fundamentals than if you move up the neck a bit - that's why the same note on the E string (played up 5 more frets) sounds "bassier" than the same note played low on the A string.
2) The harmonics are, depending on where the pickup(s) are located, filtered by this curve - when a harmonic is in a dip, it's gone. When it isn't, it's output depends on whether it's at a peak, or off to one side.
3) The "scoop" that we talk about on a J is that wider dip - about 500 Hz on this string (it is in a different place on every string). Also the lower output at low frequencies on the J curve is because you're averaging two pickups - the bridge one has less low end than the neck one, so the average is less than a neck pickup alone (aka P).
So, the timbre of a string is highly dependent on this comb filter - it's how the harmonics interact with that filter that makes a pickup location sound the way it does. If you look at the other things that affect the sound of a bass, at low and lower mid frequencies, it's almost all comb filtering/pickup locations - The locations of the nodes and antinodes of the fundamental and harmonics are (in the bass and lower mids) why different pickup locations sound different.