So many great thoughts already on this subject. I'm jumping in becuase I happen to use a LH500 with XL410 and XL210 for my rig.
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Rig:
The whole volume thing has me a bit skeptical. While I do run the extra cab, that's mainly to get speakers closer to my head than just blasting the back of my legs. Step away from your amp and listen from where the audience will be located. The LH500 is a loud amp and I do play in a rock band with 2 guitarists and a whack-em-like-there's-no-tomorrow drummer. I tend to run my volume at...wait for it....1. Not 1 o'clock, just 1. Maybe 1.5 if both guitars are playing with a bunch of distortion for a Metallica or Megadeth tune. For practice my volume is just the amp and cabs. For playing out, the LH500 has a DI so you can send your signal to the PA and still don't need to overdrive the amp. I run my amp EQ flat, and use pre-amps for tone shaping.
Bass:
I couldn't agree more witht the other comments about getting your bass adjusted...action, neck relief and pickup height. Elimnate variables by using a second bass to see if the the issue is the bass, the amp, or the cab.
Final thoughts:
I was using a craptaclar 40-watt Crate house amp in a previous band and it would fart out when I used an active eq bass. Everything was fine if I used a passive bass. Eliminate one variable at a time and you'll find your answer.